K13-MEDIATED REDUCED SUSCEPTIBILITY TO ARTEMISININ IN PLASMODIUM FALCIPARUM IS OVERLAID ON A TRAIT OF ENHANCED DNA DAMAGE REPAIR

K13-Mediated Reduced Susceptibility to Artemisinin in Plasmodium falciparum Is Overlaid on a Trait of Enhanced DNA Damage Repair

Summary: Southeast Asia has been the hotbed for the development of drug-resistant malaria parasites, including those with resistance to artemisinin combination therapy.While UBIQUINOL 100MG mutations in the kelch propeller domain (K13 mutations) are associated with artemisinin resistance, a range of evidence suggests that other factors are critical

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